diff --git a/include/OpenColorIO/OpenColorTransforms.h b/include/OpenColorIO/OpenColorTransforms.h
index 94dc58d0d6..a30af71f9b 100644
--- a/include/OpenColorIO/OpenColorTransforms.h
+++ b/include/OpenColorIO/OpenColorTransforms.h
@@ -1532,6 +1532,35 @@ class OCIOEXPORT GroupTransform : public Transform
 public:
     static GroupTransformRcPtr Create();
 
+    /**
+     * \brief Parse the contents of a LUT file contained in a memory buffer and return the
+     * transforms it contains as a GroupTransform.
+     *
+     * This allows any of the LUT file formats supported by FileTransform to be parsed from
+     * memory rather than from a file on disk.  The buffer contents is tried against each of
+     * the LUT file readers until one of them is able to parse it (the same fallback behavior
+     * that FileTransform uses for files with an unrecognized extension).  The available
+     * readers may be listed using FileTransform::GetNumFormats and
+     * FileTransform::GetFormatNameByIndex.
+     *
+     * The buffer contents are copied internally, so the buffer only needs to remain valid
+     * for the duration of the call.
+     *
+     * The parsed contents are stored in the global (process-wide) file cache, keyed on a hash
+     * of the buffer contents, so parsing a buffer with identical contents again is a cache
+     * hit.  As with LUT files loaded from disk, the cache may be flushed using
+     * \ref ClearAllCaches.
+     *
+     * \param buffer Pointer to the in-memory contents of the LUT file.
+     * \param bufferSize Size of the buffer, in bytes.
+     *
+     * \return The GroupTransform containing the parsed transforms.
+     *
+     * \throw Exception if the buffer is null or empty, or if none of the LUT file readers
+     * are able to parse the buffer contents.
+     */
+    static GroupTransformRcPtr ParseFromBuffer(const char * buffer, size_t bufferSize);
+
     virtual const FormatMetadata & getFormatMetadata() const noexcept = 0;
     virtual FormatMetadata & getFormatMetadata() noexcept = 0;
 
diff --git a/src/OpenColorIO/transforms/GroupTransform.cpp b/src/OpenColorIO/transforms/GroupTransform.cpp
index 89ba45c267..965d2f5f7f 100755
--- a/src/OpenColorIO/transforms/GroupTransform.cpp
+++ b/src/OpenColorIO/transforms/GroupTransform.cpp
@@ -7,6 +7,7 @@
 #include <OpenColorIO/OpenColorIO.h>
 
 #include "ContextVariableUtils.h"
+#include "HashUtils.h"
 #include "OpBuilders.h"
 #include "transforms/FileTransform.h"
 #include "transforms/GroupTransform.h"
@@ -14,11 +15,89 @@
 
 namespace OCIO_NAMESPACE
 {
+
+namespace
+{
+// ConfigIOProxy implementation that provides the contents of a single in-memory LUT file
+// buffer, regardless of the file path being requested.
+class BufferConfigIOProxy : public ConfigIOProxy
+{
+public:
+    BufferConfigIOProxy(const char * buffer, size_t bufferSize, const std::string & hash)
+        : m_buffer(reinterpret_cast<const uint8_t *>(buffer),
+                   reinterpret_cast<const uint8_t *>(buffer) + bufferSize)
+        , m_hash(hash)
+    {
+    }
+
+    std::vector<uint8_t> getLutData(const char * /* filepath */) const override
+    {
+        return m_buffer;
+    }
+
+    std::string getConfigData() const override
+    {
+        // Unused, the config itself is not provided through the proxy.
+        return "";
+    }
+
+    std::string getFastLutFileHash(const char * /* filepath */) const override
+    {
+        return m_hash;
+    }
+
+private:
+    std::vector<uint8_t> m_buffer;
+    std::string m_hash;
+};
+} // anonymous namespace
+
 GroupTransformRcPtr GroupTransform::Create()
 {
     return GroupTransformRcPtr(new GroupTransformImpl(), &GroupTransformImpl::Deleter);
 }
 
+GroupTransformRcPtr GroupTransform::ParseFromBuffer(const char * buffer, size_t bufferSize)
+{
+    if (!buffer || bufferSize == 0)
+    {
+        throw Exception("GroupTransform::ParseFromBuffer: buffer is null or empty.");
+    }
+
+    // Hash the buffer contents. The hash is used both to form the synthetic file name given
+    // to the FileTransform and as the fast LUT file hash returned by the ConfigIOProxy, so
+    // that the global file caches (which are keyed on these strings) never confuse the
+    // contents of two different buffers.
+    const std::string contentHash = CacheIDHash(buffer, bufferSize);
+
+    ConfigIOProxyRcPtr ciop = std::make_shared<BufferConfigIOProxy>(buffer,
+                                                                    bufferSize,
+                                                                    contentHash);
+
+    ConfigRcPtr config = Config::CreateRaw()->createEditableCopy();
+    config->setConfigIOProxy(ciop);
+
+    // Prefix the hash to form a synthetic file name so that the global file cache entries
+    // created here can never collide with those of a real file whose resolved path happens
+    // to match the bare hash string.
+    const std::string syntheticFileName = "ParseFromBuffer:" + contentHash;
+
+    FileTransformRcPtr fileTransform = FileTransform::Create();
+    fileTransform->setSrc(syntheticFileName.c_str());
+
+    try
+    {
+        ConstProcessorRcPtr processor = config->getProcessor(fileTransform);
+        return processor->createGroupTransform();
+    }
+    catch (Exception & e)
+    {
+        std::ostringstream os;
+        os << "GroupTransform::ParseFromBuffer: Error parsing LUT from buffer: " << e.what();
+        throw Exception(os.str().c_str());
+    }
+}
+
 void GroupTransformImpl::Deleter(GroupTransform * t)
 {
     delete static_cast<GroupTransformImpl *>(t);
diff --git a/src/bindings/python/transforms/PyGroupTransform.cpp b/src/bindings/python/transforms/PyGroupTransform.cpp
index 2b5757427f..0e30c1e460 100644
--- a/src/bindings/python/transforms/PyGroupTransform.cpp
+++ b/src/bindings/python/transforms/PyGroupTransform.cpp
@@ -57,6 +57,13 @@ void bindPyGroupTransform(py::module & m)
              "direction"_a = DEFAULT->getDirection(),
              DOC(GroupTransform, Create))
 
+        .def_static("ParseFromBuffer", [](const std::string & buffer)
+            {
+                return GroupTransform::ParseFromBuffer(buffer.data(), buffer.size());
+            },
+             "buffer"_a.none(false),
+             DOC(GroupTransform, ParseFromBuffer))
+
         .def_static("GetWriteFormats", []()
             {
                 return WriteFormatIterator(nullptr);
diff --git a/tests/cpu/transforms/GroupTransform_tests.cpp b/tests/cpu/transforms/GroupTransform_tests.cpp
index 67a0f656df..2bb86b14a0 100644
--- a/tests/cpu/transforms/GroupTransform_tests.cpp
+++ b/tests/cpu/transforms/GroupTransform_tests.cpp
@@ -114,3 +114,95 @@ OCIO_ADD_TEST(GroupTransform, write_with_noops)
         OCIO_CHECK_NO_THROW(group->write(config, OCIO::FILEFORMAT_CLF, oss));
     }
 }
+
+namespace
+{
+std::string ReadTestFile(const std::string & fileName)
+{
+    const std::string filePath(OCIO::GetTestFilesDir() + "/" + fileName);
+
+    std::ifstream fstream;
+    OCIO::Platform::OpenInputFileStream(fstream,
+                                        filePath.c_str(),
+                                        std::ios_base::in | std::ios_base::binary);
+    if (fstream.fail())
+    {
+        std::ostringstream os;
+        os << "Error opening test file: " << filePath;
+        throw OCIO::Exception(os.str().c_str());
+    }
+
+    std::stringstream buffer;
+    buffer << fstream.rdbuf();
+    return buffer.str();
+}
+}
+
+OCIO_ADD_TEST(GroupTransform, parse_from_buffer)
+{
+    // Parse a SPI1D LUT from a memory buffer.
+    {
+        const std::string content = ReadTestFile("lut1d_1.spi1d");
+
+        OCIO::GroupTransformRcPtr group;
+        OCIO_CHECK_NO_THROW(group = OCIO::GroupTransform::ParseFromBuffer(content.c_str(),
+                                                                          content.size()));
+        OCIO_REQUIRE_ASSERT(group);
+        OCIO_REQUIRE_EQUAL(group->getNumTransforms(), 1);
+
+        auto lut = OCIO_DYNAMIC_POINTER_CAST<const OCIO::Lut1DTransform>(group->getTransform(0));
+        OCIO_REQUIRE_ASSERT(lut);
+        OCIO_CHECK_EQUAL(lut->getLength(), 512U);
+
+        float r = 0.f, g = 0.f, b = 0.f;
+        lut->getValue(1, r, g, b);
+        OCIO_CHECK_CLOSE(r, 0.00195695f, 1e-8f);
+        OCIO_CHECK_CLOSE(g, 0.00195695f, 1e-8f);
+        OCIO_CHECK_CLOSE(b, 0.00195695f, 1e-8f);
+
+        // Parsing the same buffer again works and gives the same result.
+        OCIO::GroupTransformRcPtr group2;
+        OCIO_CHECK_NO_THROW(group2 = OCIO::GroupTransform::ParseFromBuffer(content.c_str(),
+                                                                           content.size()));
+        OCIO_REQUIRE_ASSERT(group2);
+        OCIO_REQUIRE_EQUAL(group2->getNumTransforms(), 1);
+    }
+
+    // Parse a CLF LUT from a memory buffer. This also validates that a different buffer
+    // parsed within the same process is not confused with the previous one by the global
+    // file caches.
+    {
+        const std::string content = ReadTestFile("clf/lut1d_example.clf");
+
+        OCIO::GroupTransformRcPtr group;
+        OCIO_CHECK_NO_THROW(group = OCIO::GroupTransform::ParseFromBuffer(content.c_str(),
+                                                                          content.size()));
+        OCIO_REQUIRE_ASSERT(group);
+        OCIO_REQUIRE_EQUAL(group->getNumTransforms(), 1);
+
+        auto lut = OCIO_DYNAMIC_POINTER_CAST<const OCIO::Lut1DTransform>(group->getTransform(0));
+        OCIO_REQUIRE_ASSERT(lut);
+        OCIO_CHECK_EQUAL(lut->getLength(), 65U);
+    }
+
+    // Null or empty buffer must throw.
+    {
+        OCIO_CHECK_THROW_WHAT(OCIO::GroupTransform::ParseFromBuffer(nullptr, 0),
+                              OCIO::Exception,
+                              "buffer is null or empty");
+
+        const std::string content = ReadTestFile("lut1d_1.spi1d");
+        OCIO_CHECK_THROW_WHAT(OCIO::GroupTransform::ParseFromBuffer(content.c_str(), 0),
+                              OCIO::Exception,
+                              "buffer is null or empty");
+    }
+
+    // Malformed buffer contents must throw rather than crash or silently succeed.
+    {
+        const std::string content = "This is not the content of any supported LUT format.";
+        OCIO_CHECK_THROW_WHAT(OCIO::GroupTransform::ParseFromBuffer(content.c_str(),
+                                                                    content.size()),
+                              OCIO::Exception,
+                              "Error parsing LUT from buffer");
+    }
+}
diff --git a/tests/python/GroupTransformTest.py b/tests/python/GroupTransformTest.py
index cf3820cb32..19e9a18e76 100644
--- a/tests/python/GroupTransformTest.py
+++ b/tests/python/GroupTransformTest.py
@@ -1,9 +1,11 @@
 # SPDX-License-Identifier: BSD-3-Clause
 # Copyright Contributors to the OpenColorIO Project.
 
+import os
 import unittest
 
 import PyOpenColorIO as OCIO
+from UnitTestUtils import TEST_DATAFILES_DIR
 from TransformsBaseTest import TransformsBaseTest
 
 
@@ -131,6 +133,28 @@ def test_constructor_wrong_parameter_type(self):
             with self.assertRaises(TypeError):
                 group_tr = OCIO.FixedFunctionTransform(invalid)
 
+    def test_parse_from_buffer(self):
+        """
+        Test the ParseFromBuffer() static method.
+        """
+
+        test_file = os.path.join(TEST_DATAFILES_DIR, 'lut1d_1.spi1d')
+        with open(test_file, 'rb') as f:
+            content = f.read()
+
+        group_tr = OCIO.GroupTransform.ParseFromBuffer(content)
+        self.assertEqual(len(group_tr), 1)
+        self.assertIsInstance(group_tr[0], OCIO.Lut1DTransform)
+
+        # An empty buffer raises.
+        with self.assertRaises(OCIO.Exception):
+            OCIO.GroupTransform.ParseFromBuffer(b'')
+
+        # Contents that no LUT file reader can parse raises.
+        with self.assertRaises(OCIO.Exception):
+            OCIO.GroupTransform.ParseFromBuffer(
+                b'This is not the content of any supported LUT format.')
+
     def test_write_clf(self):
         """
         Test write().