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_posts/2026-4-17-mimic.md

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@@ -10,7 +10,7 @@ blurb: Jointly modeling the entire central dogma of molecular biology - DNA, RNA
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shortblurb: Jointly modeling the entire central dogma of molecular biology - DNA, RNA, and proteins - in a single multimodal foundation model.
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splashimage: /images/blog/mimic/mimic-splash.jpg
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link: https://arxiv.org/abs/2604.24506
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github_link: https://github.com/PolymathicAI
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github_link: https://github.com/PolymathicAI/MIMIC/
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permalink: /blog/mimic/
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---
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## How MIMIC works
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<br>
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MIMIC is a billion-parameter encoder-decoder transformer trained to jointly model molecular data of the central dogma. **Where most biological AI models take a *single* type of input and produce a *single* type of output, MIMIC is designed to take in *any available* molecular information is available and generate what is missing.** Protein surface geometry, RNA splice patterns, evolutionary conservation scores, and natural language descriptions of experimental conditions are all first-class inputs and outputs within the same model.
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MIMIC is a billion-parameter encoder-decoder transformer trained to jointly model molecular data of the central dogma. **Where most biological AI models take a *single* type of input and produce a *single* type of output, MIMIC is designed to take in *any available* molecular information and generate what is missing.** Protein surface geometry, RNA splice patterns, evolutionary conservation scores, and natural language descriptions of experimental conditions are all first-class inputs and outputs within the same model.
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<p align="center" style="margin: 1.5rem 0;">
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<img style="width: 95%; max-width: 900px;" src="/images/blog/mimic/MIMIC_architecture.png" alt="MIMIC architecture">
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### Open Source Resources
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<br>
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We are currently preparing MIMIC code and weights for public release. We are also preparing LORE for public release, including data clustering, splits, and pre-computed tokenization. Upon release, both the MIMIC model and the LORE dataset will be available on the [Polymathic AI GitHub](https://github.com/PolymathicAI).
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We are currently preparing MIMIC code and weights for public release. We are also preparing LORE for public release, including data clustering, splits, and pre-computed tokenization. Upon release, both the MIMIC model and the LORE dataset will be available on the [Polymathic AI GitHub](https://github.com/PolymathicAI/MIMIC/).
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*-- Sophie Barstein, Samuel Sledzieski, Jake Kovalic*
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