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DESCRIPTION
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Package: metaLINCS
Title: Meta-analysis of LINCS L1000 drug signatures using stratified connectivity mapping
Version: 0.9.0
Authors@R: c(
person("Ivo", "Kwee", , "kwee@bigomics.ch", role = "aut",
comment = c(ORCID = "0000-0002-2751-4218")),
person("Layal", "Abo Khayal", , "layal.abo.khayal@gmail.com", role = "cre")
)
Description: 'metaLINCS' calculates and visualises correlation between
experimental gene expression profiles with pertubation signatures from
the LINCS L1000 project that has collected gene expression profiles
for thousands of perturbagens at a variety of time points, doses, and
cell lines.
License: GPL (>= 3)
URL: https://github.com/bigomics/metaLINCS
BugReports: https://github.com/bigomics/metaLINCS/issues
Depends:
R (>= 3.5.0)
Imports:
corrplot,
fgsea,
gplots,
graphics,
Matrix,
qlcMatrix,
stats,
utils,
uwot
Suggests:
knitr,
rmarkdown,
testthat (>= 3.0.0)
VignetteBuilder:
knitr
Config/testthat/edition: 3
Encoding: UTF-8
LazyData: true
LazyDataCompression: bzip2
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.0