diff --git a/rest_framework/compat.py b/rest_framework/compat.py
index 5fad483911..4a11b8d4ce 100644
--- a/rest_framework/compat.py
+++ b/rest_framework/compat.py
@@ -189,6 +189,18 @@ def get_referenced_base_fields_from_q(q):
         }
 
 
+if django.VERSION >= (6, 1):
+    # `split_header_value` was added in Django 6.2 (backported to 6.1b1+),
+    # replacing the `cc_delim_re` regular expression.
+    # https://github.com/django/django/commit/526b1b414d8e215bf627b5722df12a09346dbf6b
+    from django.utils.http import split_header_value
+else:
+
+    def split_header_value(value, sep=","):
+        for part in value.split(sep):
+            if stripped := part.strip():
+                yield stripped
+
 # `separators` argument to `json.dumps()` differs between 2.x and 3.x
 # See: https://bugs.python.org/issue22767
 SHORT_SEPARATORS = (',', ':')
diff --git a/rest_framework/views.py b/rest_framework/views.py
index 327ebe9032..1439570d46 100644
--- a/rest_framework/views.py
+++ b/rest_framework/views.py
@@ -7,12 +7,13 @@
 from django.db import connections, models
 from django.http import Http404
 from django.http.response import HttpResponseBase
-from django.utils.cache import cc_delim_re, patch_vary_headers
+from django.utils.cache import patch_vary_headers
 from django.utils.encoding import smart_str
 from django.views.decorators.csrf import csrf_exempt
 from django.views.generic import View
 
 from rest_framework import exceptions, status
+from rest_framework.compat import split_header_value
 from rest_framework.request import Request
 from rest_framework.response import Response
 from rest_framework.schemas import DefaultSchema
@@ -444,7 +445,7 @@ def finalize_response(self, request, response, *args, **kwargs):
         # Add new vary headers to the response instead of overwriting.
         vary_headers = self.headers.pop('Vary', None)
         if vary_headers is not None:
-            patch_vary_headers(response, cc_delim_re.split(vary_headers))
+            patch_vary_headers(response, split_header_value(vary_headers))
 
         for key, value in self.headers.items():
             response[key] = value