diff --git a/packages/react-native/Libraries/Components/View/ReactNativeViewAttributes.js b/packages/react-native/Libraries/Components/View/ReactNativeViewAttributes.js
index f349a0a9b0a7..e494e151a019 100644
--- a/packages/react-native/Libraries/Components/View/ReactNativeViewAttributes.js
+++ b/packages/react-native/Libraries/Components/View/ReactNativeViewAttributes.js
@@ -44,6 +44,7 @@ const UIView = {
   mouseDownCanMoveWindow: true,
   enableFocusRing: true,
   focusable: true,
+  onAuxClick: true,
   onMouseEnter: true,
   onMouseLeave: true,
   onDoubleClick: true,
diff --git a/packages/react-native/Libraries/Components/View/ViewPropTypes.js b/packages/react-native/Libraries/Components/View/ViewPropTypes.js
index d8281aaf7fb6..b495fe687720 100644
--- a/packages/react-native/Libraries/Components/View/ViewPropTypes.js
+++ b/packages/react-native/Libraries/Components/View/ViewPropTypes.js
@@ -135,6 +135,8 @@ type MouseEventProps = $ReadOnly<{
 
 // Experimental/Work in Progress Pointer Event Callbacks (not yet ready for use)
 type PointerEventProps = $ReadOnly<{
+  onAuxClick?: ?(event: PointerEvent) => void,
+  onAuxClickCapture?: ?(event: PointerEvent) => void,
   onClick?: ?(event: PointerEvent) => void,
   onClickCapture?: ?(event: PointerEvent) => void,
   onPointerEnter?: ?(event: PointerEvent) => void,
diff --git a/packages/react-native/Libraries/NativeComponent/BaseViewConfig.ios.js b/packages/react-native/Libraries/NativeComponent/BaseViewConfig.ios.js
index 5c96ddeabeff..0cda0bf11cb1 100644
--- a/packages/react-native/Libraries/NativeComponent/BaseViewConfig.ios.js
+++ b/packages/react-native/Libraries/NativeComponent/BaseViewConfig.ios.js
@@ -89,6 +89,12 @@ const bubblingEventTypes = {
   },
 
   // Experimental/Work in Progress Pointer Events (not yet ready for use)
+  topAuxClick: {
+    phasedRegistrationNames: {
+      captured: 'onAuxClickCapture',
+      bubbled: 'onAuxClick',
+    },
+  },
   topClick: {
     phasedRegistrationNames: {
       captured: 'onClickCapture',
@@ -394,6 +400,8 @@ const validAttributesForEventProps = ConditionallyIgnoredEventHandlers({
   onTouchCancel: true,
 
   // Pointer events
+  onAuxClick: true,
+  onAuxClickCapture: true,
   onClick: true,
   onClickCapture: true,
   onPointerUp: true,
diff --git a/packages/react-native/Libraries/Pressability/Pressability.js b/packages/react-native/Libraries/Pressability/Pressability.js
index 39609d8b9a24..b5d6fd9e4103 100644
--- a/packages/react-native/Libraries/Pressability/Pressability.js
+++ b/packages/react-native/Libraries/Pressability/Pressability.js
@@ -554,6 +554,14 @@ export default class Pressability {
           return;
         }
 
+        // [macOS Only fire onPress for primary (left) mouse button clicks.
+        // Non-primary buttons (right, middle) should not trigger onPress.
+        const button = event?.nativeEvent?.button;
+        if (button != null && button !== 0) {
+          return;
+        }
+        // macOS]
+
         // for non-pointer click events (e.g. accessibility clicks), we should only dispatch when we're the "real" target
         // in particular, we shouldn't respond to clicks from nested pressables
         if (event?.currentTarget !== event?.target) {
diff --git a/packages/react-native/React/Fabric/Mounting/ComponentViews/View/RCTViewComponentView.mm b/packages/react-native/React/Fabric/Mounting/ComponentViews/View/RCTViewComponentView.mm
index 1e31f460f8a9..032bb16ce505 100644
--- a/packages/react-native/React/Fabric/Mounting/ComponentViews/View/RCTViewComponentView.mm
+++ b/packages/react-native/React/Fabric/Mounting/ComponentViews/View/RCTViewComponentView.mm
@@ -2032,9 +2032,10 @@ - (BOOL)performDragOperation:(id <NSDraggingInfo>)sender
   MouseEnter,
   MouseLeave,
   DoubleClick,
+  AuxClick,
 };
 
-- (void)emitMouseEvent:(MouseEventType)eventType
+- (void)emitMouseEvent:(MouseEventType)eventType button:(int)button
 {
   if (!_eventEmitter) {
     return;
@@ -2054,6 +2055,7 @@ - (void)emitMouseEvent:(MouseEventType)eventType
     .ctrlKey = static_cast<bool>(modifierFlags & NSEventModifierFlagControl),
     .shiftKey = static_cast<bool>(modifierFlags & NSEventModifierFlagShift),
     .metaKey = static_cast<bool>(modifierFlags & NSEventModifierFlagCommand),
+    .button = button,
   };
 
   switch (eventType) {
@@ -2068,9 +2070,18 @@ - (void)emitMouseEvent:(MouseEventType)eventType
     case DoubleClick:
       _eventEmitter->onDoubleClick(mouseEvent);
       break;
+
+    case AuxClick:
+      _eventEmitter->onAuxClick(mouseEvent);
+      break;
   }
 }
 
+- (void)emitMouseEvent:(MouseEventType)eventType
+{
+  [self emitMouseEvent:eventType button:0];
+}
+
 - (void)updateMouseOverIfNeeded
 {
   // When an enclosing scrollview is scrolled using the scrollWheel or trackpad,
@@ -2191,6 +2202,16 @@ - (void)mouseUp:(NSEvent *)event
     [super mouseUp:event];
   }
 }
+
+- (void)rightMouseUp:(NSEvent *)event
+{
+  BOOL hasAuxClickEventHandler = _props->hostPlatformEvents[HostPlatformViewEvents::Offset::AuxClick];
+  if (hasAuxClickEventHandler) {
+    [self emitMouseEvent:AuxClick button:2];
+  } else {
+    [super rightMouseUp:event];
+  }
+}
 #endif // macOS]
 
 - (SharedTouchEventEmitter)touchEventEmitterAtPoint:(CGPoint)point
diff --git a/packages/react-native/React/Fabric/RCTSurfacePointerHandler.mm b/packages/react-native/React/Fabric/RCTSurfacePointerHandler.mm
index 8536d3284792..308c14de42d2 100644
--- a/packages/react-native/React/Fabric/RCTSurfacePointerHandler.mm
+++ b/packages/react-native/React/Fabric/RCTSurfacePointerHandler.mm
@@ -703,8 +703,12 @@ - (void)_dispatchActivePointers:(std::vector<ActivePointer>)activePointers event
         }
         case RCTPointerEventTypeEnd: {
           eventEmitter->onPointerUp(pointerEvent);
-          if (pointerEvent.isPrimary && pointerEvent.button == 0 && IsPointerWithinInitialTree(activePointer)) {
-            eventEmitter->onClick(std::move(pointerEvent));
+          if (pointerEvent.isPrimary && pointerEvent.button == 0) {
+            if (IsPointerWithinInitialTree(activePointer)) {
+              eventEmitter->onClick(std::move(pointerEvent));
+            }
+          } else if (IsPointerWithinInitialTree(activePointer)) {
+            eventEmitter->onAuxClick(std::move(pointerEvent));
           }
           break;
         }
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.cpp b/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.cpp
index 6264d5fe50d6..3a390c6bd886 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.cpp
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.cpp
@@ -86,6 +86,10 @@ void TouchEventEmitter::onTouchCancel(TouchEvent event) const {
       "touchCancel", std::move(event), RawEvent::Category::ContinuousEnd);
 }
 
+void TouchEventEmitter::onAuxClick(PointerEvent event) const {
+  dispatchPointerEvent("auxClick", std::move(event), RawEvent::Category::Discrete);
+}
+
 void TouchEventEmitter::onClick(PointerEvent event) const {
   dispatchPointerEvent("click", std::move(event), RawEvent::Category::Discrete);
 }
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.h b/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.h
index e7dcfa7d84aa..60ce1dd8a424 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/TouchEventEmitter.h
@@ -29,6 +29,7 @@ class TouchEventEmitter : public EventEmitter {
   void onTouchEnd(TouchEvent event) const;
   void onTouchCancel(TouchEvent event) const;
 
+  void onAuxClick(PointerEvent event) const;
   void onClick(PointerEvent event) const;
   void onPointerCancel(PointerEvent event) const;
   void onPointerDown(PointerEvent event) const;
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.cpp b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.cpp
index 357ab6917ef5..6ed3d0d84274 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.cpp
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.cpp
@@ -63,6 +63,7 @@ static jsi::Object mouseEventPayload(jsi::Runtime& runtime, const MouseEvent& ev
   payload.setProperty(runtime, "ctrlKey", event.ctrlKey);
   payload.setProperty(runtime, "shiftKey", event.shiftKey);
   payload.setProperty(runtime, "metaKey", event.metaKey);
+  payload.setProperty(runtime, "button", event.button);
   return payload;
 };
 
@@ -84,6 +85,12 @@ void HostPlatformViewEventEmitter::onDoubleClick(const MouseEvent& mouseEvent) c
   });
 }
 
+void HostPlatformViewEventEmitter::onAuxClick(const MouseEvent& mouseEvent) const {
+  dispatchEvent("auxClick", [mouseEvent](jsi::Runtime& runtime) {
+    return mouseEventPayload(runtime, mouseEvent);
+  });
+}
+
 #pragma mark - Drag and Drop Events
 
 jsi::Value HostPlatformViewEventEmitter::dataTransferPayload(
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.h b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.h
index c5587906a519..f0f4e912f66b 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEventEmitter.h
@@ -34,6 +34,7 @@ class HostPlatformViewEventEmitter : public BaseViewEventEmitter {
   void onMouseEnter(MouseEvent const& mouseEvent) const;
   void onMouseLeave(MouseEvent const& mouseEvent) const;
   void onDoubleClick(MouseEvent const& mouseEvent) const;
+  void onAuxClick(MouseEvent const& mouseEvent) const;
 
 #pragma mark - Drag and Drop Events
 
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEvents.h b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEvents.h
index cefa27d007a3..a180e9c2ebd3 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEvents.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/HostPlatformViewEvents.h
@@ -30,6 +30,7 @@ struct HostPlatformViewEvents {
     MouseEnter = 4,
     MouseLeave = 5,
     DoubleClick = 6,
+    AuxClick = 7,
   };
 
   constexpr bool operator[](const Offset offset) const {
@@ -74,6 +75,8 @@ static inline HostPlatformViewEvents convertRawProp(
       convertRawProp(context, rawProps, "onMouseLeave", sourceValue[Offset::MouseLeave], defaultValue[Offset::MouseLeave]);
   result[Offset::DoubleClick] =
       convertRawProp(context, rawProps, "onDoubleClick", sourceValue[Offset::DoubleClick], defaultValue[Offset::DoubleClick]);
+  result[Offset::AuxClick] =
+      convertRawProp(context, rawProps, "onAuxClick", sourceValue[Offset::AuxClick], defaultValue[Offset::AuxClick]);
 
   return result;
 }
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/MouseEvent.h b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/MouseEvent.h
index 334506c93adc..a53210a409d4 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/MouseEvent.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/platform/macos/react/renderer/components/view/MouseEvent.h
@@ -54,6 +54,14 @@ struct MouseEvent {
    * A flag indicating if the meta key is pressed.
    */
   bool metaKey{false};
+
+  /**
+   * The button number that was pressed when the mouse event was fired:
+   *  0 = primary button (usually the left button)
+   *  1 = auxiliary button (usually the middle/wheel button)
+   *  2 = secondary button (usually the right button)
+   */
+  int button{0};
 };
 
 struct DataTransferFile {
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/primitives.h b/packages/react-native/ReactCommon/react/renderer/components/view/primitives.h
index 8ec8e1ab29be..290d2b4bc3ab 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/primitives.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/primitives.h
@@ -67,6 +67,8 @@ struct ViewEvents {
     PointerDownCapture = 35,
     PointerUp = 36,
     PointerUpCapture = 37,
+    AuxClick = 38,
+    AuxClickCapture = 39,
   };
 
   constexpr bool operator[](const Offset offset) const {
diff --git a/packages/react-native/ReactCommon/react/renderer/components/view/propsConversions.h b/packages/react-native/ReactCommon/react/renderer/components/view/propsConversions.h
index 74dcc8f16420..e15c33572222 100644
--- a/packages/react-native/ReactCommon/react/renderer/components/view/propsConversions.h
+++ b/packages/react-native/ReactCommon/react/renderer/components/view/propsConversions.h
@@ -830,6 +830,10 @@ static inline ViewEvents convertRawProp(
       "onPointerOutCapture",
       sourceValue[Offset::PointerOutCapture],
       defaultValue[Offset::PointerOutCapture]);
+  result[Offset::AuxClick] =
+      convertRawProp(context, rawProps, "onAuxClick", sourceValue[Offset::AuxClick], defaultValue[Offset::AuxClick]);
+  result[Offset::AuxClickCapture] = convertRawProp(
+      context, rawProps, "onAuxClickCapture", sourceValue[Offset::AuxClickCapture], defaultValue[Offset::AuxClickCapture]);
   result[Offset::Click] = convertRawProp(
       context,
       rawProps,
diff --git a/packages/react-native/ReactNativeApi.d.ts b/packages/react-native/ReactNativeApi.d.ts
index c02c6ddd74ff..999c3f8916a2 100644
--- a/packages/react-native/ReactNativeApi.d.ts
+++ b/packages/react-native/ReactNativeApi.d.ts
@@ -3676,6 +3676,8 @@ declare type PlatformType =
   | WindowsPlatform
 declare type PointerEvent = NativeSyntheticEvent<NativePointerEvent>
 declare type PointerEventProps = {
+  readonly onAuxClick?: (event: PointerEvent) => void
+  readonly onAuxClickCapture?: (event: PointerEvent) => void
   readonly onClick?: (event: PointerEvent) => void
   readonly onClickCapture?: (event: PointerEvent) => void
   readonly onGotPointerCapture?: (e: PointerEvent) => void
diff --git a/packages/rn-tester/js/examples/Pressable/PressableExample.js b/packages/rn-tester/js/examples/Pressable/PressableExample.js
index 47211b7c8283..a69ca61b4f32 100644
--- a/packages/rn-tester/js/examples/Pressable/PressableExample.js
+++ b/packages/rn-tester/js/examples/Pressable/PressableExample.js
@@ -131,6 +131,7 @@ function PressableFeedbackEvents() {
           onDragLeave={() => appendEvent('dragLeave')}
           onDrop={() => appendEvent('drop')}
           draggedTypes={'fileUrl'}
+          onAuxClick={() => appendEvent('auxClick')}
           onDoubleClick={() => appendEvent('doubleClick')}
           // macOS]
           onPress={() => appendEvent('press')}