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<h1>Gene Regulation of Cell identity LAB</h1>
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<li><a href="researchprojects.html">RESEARCH PROJECTS</a></li>
<li><a href="publications.html">PUBLICATIONS</a></li>
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<Div class="publicationswrap">
<h1>Publications</h1>
<div class="publications 25">
<h3>2025</h3>
<div class="publication">
<p><strong>Staufen2 modulates the temporal dynamics of human neurogenesis <em>in vitro</em></strong></p>
<p><strong>Akshay Jaya ganesh, Sandra María Fernández-Moya,
Ana Gutierrez-Franco, Natalie Chaves Ferreira,
Rafael Tur-Guasch</strong>, Damia Romero-Moya, Alessandra Giorgetti, Loris Mularoni, Monika Piwecka, Agnieszka Rybak-Wolf,
<strong>Mireya Plass</strong></p>
<p><em>BioRxiv 2025.10.02.679988</em></p>
<p><a href="https://www.biorxiv.org/content/10.1101/2025.10.02.679988v1.abstract">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>Astrocytic Ceruloplasmin Deficiency Triggers Iron Toxicity and Neurodegeneration in a LRRK2 Parkinson's Tri-Culture Model</strong></p>
<p>Veronica Testa, Jara Montero-Muñoz, Valentina Baruffi, Marieke Alzeer, Loris Mularoni, Irene Fernández-Carasa, Giulia
Simmini, Núria
Comellas-Comaposada, <strong>Franz Arnold
Ake</strong>, Yvonne Richaud, Christin
Weissleder, Josep Amengual, Isabel Fabregat,
Michela Deleidi,
<strong>Mireya Plass</strong>, Stefano Pluchino, Ángel Raya, Antonella Consiglio</p>
<p><em>BioRxiv 2025.08. 01.668099</em></p>
<p><a href="https://www.biorxiv.org/content/10.1101/2025.08.01.668099v1.abstract">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>CRISPR-engineered human GATA2 deficiency model uncovers mitotic dysfunction and premature aging in HSPCs, impairing hematopoietic fitness</strong></p>
<p>Damia Romero-Moya, Eric Torralba-Sales, Cristina Calvo, Oskar Marin-Bejar, Maria Magallon-Mosella,
Maximiliano Distefano, Joan Pera, Julio Castaño,
Francesca De Giorgio, Jessica Gonzalez, Arnau
Iglesias, Clara Berenguer-Balaguer,
<strong>Marcel Schilling</strong>, <strong>Mireya Plass</strong>, Lorenzo Pasquali, Albert Català, Oscar Molina, Marcin W Wlodarski, Anna Bigas, Alessandra Giorgetti</p>
<p><em>Leukemia (2025). https://doi.org/10.1038/s41375-025-02771-8</em></p>
<p><a href="https://www.nature.com/articles/s41375-025-02771-8">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>Quantification of transcript isoforms at the single-cell level using SCALPEL</strong></p>
<p><strong>Franz Ake, Marcel Schilling, Sandra Maria Fernandez-Moya, Akshay Jaya Ganesh, Ana Gutierrez-Franco, </strong> Lei Li<strong>, Mireya Plass</strong></p>
<p><em>Nature Communications 16, 6402</em></p>
<p><a href="https://www.nature.com/articles/s41467-025-61118-0"> Link to the full publication</a></p>
<p><a href="https://github.com/plasslab/SCALPEL">GitHub Repo</a></p>
</div>
</div>
<div class="publications 24">
<h3>2024</h3>
<div class="publication">
<p><strong>A distinct class of pan-cancer susceptibility genes revealed by an alternative polyadenylation transcriptome-wide association study</strong></p>
<p><strong>Hui Chen</strong>, Zeyang Wang, Lihai Gong, Qixuan Wang, Wenyan Chen, Jia Wang,
Xuelian Ma, Ruofan Ding, Xing Li, Xudong Zou, <strong>Mireya Plass</strong>, Cheng Lian, Ting Ni, Gong-Hong Wei, Wei Li, Lin Deng, Lei Li</p>
<p><em>Nature Communications 15 (1), 1729</em></p>
<p><a href="https://www.nature.com/articles/s41467-024-46064-7">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>scQTLbase: an integrated human single-cell eQTL database</strong></p>
<p>Ruofan Ding, Qixuan Wang, Lihai Gong, Ting Zhang, Xudong Zou, Kewei Xiong, Qi Liao, <strong>Mireya Plass</strong>, Lei Li</p>
<p><em>Nucleic Acids Research 52 (D1), D1010-D1017</em></p>
<p><a href="https://academic.oup.com/nar/article/52/D1/D1010/7288825?login=false">Link to the full publication</a></p>
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<!-- <div class="publication">
<p></p>
<p><strong></strong><strong></strong></p>
<p></p>
<p><a href="">Full article: <em>[posar nom títol aquí, per a que apareixi en cursiva]</em></a></p>
<p><strong>Software: </strong><a href=""><em>[posar nom enllaç aquí]</em></a></p>
</div> -->
</div>
<div class="publications 23">
<h3>2023</h3>
<div class="publication">
<P>Neural cell diversity in the light of single-cell transcriptomics
</p>
<p><strong>Sandra María Fernández-Moya, Akshay Jaya Ganesh, Mireya Plass</strong></p>
<p><em>Transcription 14 (3-5), 158-176</em></p>
<p><a href="https://www.tandfonline.com/doi/full/10.1080/21541264.2023.2295044">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>Methanol fixation is the method of choice for droplet-based single-cell transcriptomics of neural cells</strong></p>
<p><strong>Ana Gutiérrez-Franco, Franz Ake, Mohamed N Hassan, Natalie Chaves Cayuela</strong>, Loris Mularoni, <strong>Mireya Plass</strong></p>
<P><Em>Communications Biology 6 (1), 522</em></p>
<P><A Href="Https://www.nature.com/articles/s42003-023-04834-x">Link to the full publication</a></p>
</div>
</div>
<div class="publications 22">
<h3>2022</h3>
<div class="publication">
<p><strong>Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice</strong></p>
<p>Sara Montserrat-Vazquez, Noelle J Ali, Francesca Matteini, Javier Lozano, Tu Zhaowei, Eva Mejia-Ramirez, Gina Marka, Angelika Vollmer, Karin Soller, Mehmet Sacma, Vadim Sakk, Loris Mularoni, Jan Philipp Mallm, <strong>Mireya Plass</strong>, Yi Zheng, Hartmut Geiger, M Carolina Florian<strong></strong></p>
<p><em>npj Regenerative Medicine 7 (1), 78</em></p>
<p><a href="https://www.nature.com/articles/s41536-022-00275-y">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians</strong></p>
<p>Thomas Spruce, <strong>Mireya Plass</strong>, André Gohr, Debashish Ray, María Martínez de Lagrán, Gregor Rot, Ana Nóvoa, Demian Burguera, Jon Permanyer, Marta Miret, Hong Zheng, Maurice S Swanson, Quaid Morris, Moises Mallo, Mara Dierssen, Timothy R Hughes, Barbara Pernaute, Manuel Irimia</p>
<p><em>PLoS biology 20 (4), e3001615</em></p>
<p><a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001615">Link to the full publication</a></p>
</div>
</div>
<div class="publications 21">
<h3>2021</h3>
<div class="publication">
<p><strong>Heterogeneity and cancer-related features in lymphangioleiomyomatosis cells and tissue</strong></p>
<p>Roderic Espín, Alexandra Baiges, Eline Blommaert, Carmen Herranz, Antonio Roman, Berta Saez, Julio Ancochea, Claudia Valenzuela, Piedad Ussetti, Rosalía Laporta, José A Rodríguez-Portal, Coline HM van Moorsel, Joanne J van der Vis, Marian JR Quanjel, Anna Villar-Piqué, Daniela Diaz-Lucena, Franc Llorens, Álvaro Casanova, María Molina-Molina, <strong>Mireya Plass</strong>, Francesca Mateo, Joel Moss, Miquel Angel Pujana</p>
<p><em>Molecular Cancer Research 19 (11), 1840-1853</em></p>
<p><a href="https://aacrjournals.org/mcr/article/19/11/1840/672853/Heterogeneity-and-Cancer-Related-Features-in">Link to the full publication</a></p>
</div>
<div class="publication">
<p><strong>RNA Dynamics in Alzheimer's Disease</strong></p>
<p>Agnieszka Rybak-Wolf, <strong>Mireya Plass</strong></p>
<p><em>Molecules 26 (17), 5113</em></p>
<p><a href="https://www.mdpi.com/1420-3049/26/17/5113">Link to the full article</a></p>
</div>
</div>
<div class="all publications">
<p>To full list of publications by Dr. Mireya Plass</p>
<button><a target="_blank" href="https://scholar.google.es/citations?view_op=list_works&hl=es&hl=es&user=4aa200MAAAAJ&sortby=pubdate ">click here</a></button>
</div>
<!-- <div class="publications 19">
<h3>2019</h3>
<div class="publication">
<a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1663-x">PAGA: graph abstraction reconciles clustering
with trajectory inference through a topology preserving map of single cells. </a>
<p>Wolf FA, Hamey FK, Plass M, Solana J, Dahlin JS, Göttgens B, Rajewsky N, Simon L, Theis FJ.<br><span>Biol.</span></p>
</div> publication-->
<!--
</div>
<div class="publications 18">
<h3>2018</h3>
<a href="https://www.science.org/doi/10.1126/science.aaq1723"> Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics.</a>
<p>Plass M*, Solana J*, Wolf FA, Ayoub S, Misios A, Glažar P, Obermayer B, Theis FJ, Kocks C, Rajewsky N.<br><span>Science</span></p>
</div>
<div class="publications 17">
<h3>2017</h3>
<a href="https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005460">Highly accessible AU-rich regions in 3′ untranslated
regions are hotspots for binding of regulatory factors. </a>
<p>Plass M*†, Rasmussen SH*, Krogh A†<br><span>PLoS Comput Biol.</span></p>
</div>
<div class="publications 14">
<h3>2014</h3>
<a href="https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2014.00046/full">Alternative polyadenylation of tumor suppressor genes in
small intestinal neuroendocrine tumors. </a>
<p>Rehfeld A*, Plass M*, Døssing K, Knigge U, Kjær A, Krogh A, Friis-Hansen L.<br><span>Front Endocrinol (Lausanne).</span></p>
</div> -->
</div> <!----publicationswrap-->
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